A large scale profiling and analysis of glycerophospholipid species in macrophages has facilitated the identification of several rare and atypical glycerophospholipid species.By using liquid Tanks/Jerseys chromatography tandem mass spectrometry and comparison of the elution and fragmentation properties of the rare lipids to synthetic standards, we
Study on the polymorphism of POU1F1 gene in sheep
ABSTRACT In this study, POU1F1 gene polymorphism was detected in five sheep populations (large-tailed Han, small-tailed Han, Yuxi fat-tailed, Lanzhou large-tailed, and Mongolian sheep), using DNA pooling and sequencing, to provide theoretical basis for the breeding of excellent sheep varieties.Three single-nucleotide polymorphism (SNP) loci of POU1
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
Background Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis.Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as promoter hypermethylation can lead to decreased expression ROOT of BRCA1/2 in ovarian cancers.The mechanism of BRCA1/2 loss is a potential method of sub